The basis of InVenio™ technology derives from a unique discovery made by Pastel's founder and is covered in the core patents. Using publicly accessible databases Pastel's scientists have designed sophisticated algorithms and bioinformatics tools to search through the millions of protein sequences and optimise the minimal set of capture molecules that would need to be selected to uniquely identify all proteins.

Organism agnostic

The bioinformatic 'fingerprint' that Pastel uses to identify proteins is unlike any other technique being employed and allows InVenio™ technology to be completely organism agnostic. Other array based technologies that employ antibodies or aptamers are organism specific, very much limiting their utility.

Novel protein identification

Owing to the way the bioinformatic algorithms generate the protein 'fingerprint' it is possible to easily identify novel proteins that may not be present in current databases. These may result from:
unexpected splice isoforms of the organism being studied
the presence of existing and importantly novel pathogenic organisms

Post-translational modifications (PTMs)

Pastel's scientists have also demonstrated, using its in-house bioinformatics, that the presence of many of the more common post-translational modifications will also be identifiable using InVenio™ technology, significantly expanding the power of the platform to generate 'fit for purpose' biomarkers.

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